Sergey Koren, PhD

Associate Investigator

sergey.korennih.gov

Sergey received his PhD in computer science in 2012 under the supervision of Mihai Pop at the University of Maryland. He joined the National Bioforensics Analysis Center in 2011 and was appointed as an associate principal investigator in 2014. During this time, he pioneered the use of single-molecule sequencing for the reconstruction of complete genomes. In 2015, he joined the National Human Genome Research Institute as a founding member of the Genome Informatics Section. His research focuses on the efficient analysis of large-scale genomic datasets and new methods for metagenomic analysis and assembly of high-noise single-molecule sequencing data.

Software

Merqury

Evaluate genome assemblies with k-mers and more

Winnowmap

A long-read mapping algorithm optimized for mapping ONT and PacBio reads to repetitive reference sequences.

MetaMaps

Long-read metagenomic analysis

SALSA

A tool to scaffold long read assemblies with Hi-C data
News posts

Human genome assemblies with nanopore, an update

May 23, 2018

Assembling the Cliveome

April 28, 2017

Assembly of a human genome from nanopore sequencing data

January 8, 2017
Publications
The whale shark genome reveals patterns of vertebrate gene family evolution
eLife, August 19, 2021
Tan M, Redmond AK, Dooley H, Nozu R, Sato K, Kuraku S, Koren S, Phillippy AM, Dove ADM, and Read TD