Sergey Koren, PhD

Staff Scientist

sergey.korennih.gov

Sergey received his PhD in computer science in 2012 under the supervision of Mihai Pop at the University of Maryland. He joined the National Bioforensics Analysis Center in 2011 and was appointed as an associate principal investigator in 2014. During this time, he pioneered the use of single-molecule sequencing for the reconstruction of complete genomes. In 2015, he joined the National Human Genome Research Institute as a founding member of the Genome Informatics Section. His research focuses on the efficient analysis of large-scale genomic datasets and new methods for metagenomic analysis and assembly of high-noise single-molecule sequencing data.

Projects

MashMap

A fast and approximate long read mapper

Canu

A single molecule sequence assembler for genomes large and small

Mash

Fast genome and metagenome distance and containment estimation using MinHash

MHAP

A probabilistic sequence overlap algorithm
News posts

Human genome assemblies with nanopore, an update

May 23, 2018

Assembling the Cliveome

April 28, 2017

Assembly of a human genome from nanopore sequencing data

January 8, 2017
Publications
RefSeq database growth influences the accuracy of k-mer-based species identification
bioRxiv, April 19, 2018
Nasko DJ, Koren S, Phillippy AM, Treangen TJ