Arang Rhie, PhD
Staff Scientist
arang.rhienih.gov
Arang received a BS in computer science in 2009 and MS in bioinformatics in 2011 from Ewha Womans University. She completed her PhD in 2017 at the Genome Medicine Institute, Department of Biomedical Science, Seoul National University College of Medicine. Her dissertation research aimed to build the first high-quality Korean reference genome for use in medical diagnostics. After her post-doctoral training in the Genome Informatics Section at NIH/NHGRI, she is continuing her research as a staff scientist, focusing on the reconstruction and evaluation of true haplotypes from long-read sequencing and other emerging technologies. She is an active member of the Vertebrate Genomes Project (VGP), Earth Biogenome Project (EBP), Human Pangenome Reference Consortium (HPRC) and the Telomere-to-Telomere consortium (T2T).
Merqury
Evaluate genome assemblies with k-mers and more
Winnowmap
A long-read mapping algorithm optimized for mapping ONT and PacBio reads to repetitive reference sequences.
SALSA
A tool to scaffold long read assemblies with Hi-C data
Canu
A single molecule sequence assembler for genomes large and small
Telomere-to-telomere assemblies of cattle and sheep Y-chromosomes uncover divergent structure and gene content
Nature Communications, September 27, 2024
Olagunju TA, Rosen BD, Neibergs HL, Becker GM, Davenport KM, Elsik CG, Hadfield TS, Koren S, Kuhn KL, Rhie A, Shira KA, Skibiel AL, Stegemiller MR, Thorne JW, Villamediana P, Cockett NE, Murdoch BM, Smith TPL
The formation and propagation of human Robertsonian chromosomes
bioRxiv, September 26, 2024
de Lima LG, Guarracino A, Koren S, Potapova TA, McKinney SA, Rhie A, Solar SJ, Seidel C, Fagen B, Walenz BP, Bouffard GG, Brooks SY, Peterson M, Hall KE, Crawford J, Young AC, Pickett BD, Garrison E, Phillippy AM, Gerton JL
Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure
Evolution, August 29, 2024
Ishigohoka J, Bascón-Cardozo K, Bours A, Fuß J, Rhie A, Mountcastle J, Haase B, Chow W, Collins J, Howe K, Uliano-Silva M, Fedrigo O, Jarvis ED, Pérez-Tris J, Illera JC, Liedvogel M
The Ruminant Telomere to Telomere (RT2T) Consortium