Adam Phillippy, PhD

Senior Investigator

Adam is a Senior Investigator and Head of the Genome Informatics Section at the National Human Genome Research Institute (NHGRI). His lab develops efficient computational methods for analyzing DNA sequencing data, including tools for genome assembly, alignment, clustering, forensics, and metagenomics. He is a co-founder of the Telomere-to-Telomere Consortium and Vertebrate Genomes Project, which seek to enable the complete and gapless assembly of human and all other vertebrate genomes. He received a B.S. in computer science from Loyola University Maryland in 2002, where he was advised by Dr. Arthur Delcher. He first worked as a bioinformatics engineer at The Institute for Genomic Research (TIGR) with Dr. Mihai Pop, and later received a Ph.D. in computer science from the University of Maryland in 2010 with Dr. Steven Salzberg. After graduate school he led a bioinformatics group at the National Bioforensics Analysis Center before joining NHGRI in 2015. In 2019, he was awarded tenure by the NIH and received the U.S. Presidential Early Career Award for Scientists and Engineers.



Verkko is a hybrid genome assembly pipeline developed for telomere-to-telomere assembly of long accurate (e.g. PacBio HiFi) and ultra-long (e.g. Oxford Nanopore UL) reads. Verkko is Finnish for net, mesh and graph.


Evaluate genome assemblies with k-mers and more


A long-read mapping algorithm optimized for mapping ONT and PacBio reads to repetitive reference sequences.


Long-read metagenomic analysis
News posts

It's finally finished!

March 31, 2022

We are hiring!

October 27, 2021

The complete sequence of a human genome

July 23, 2021

The (near) complete sequence of a human genome

September 22, 2020
Recombination between heterologous human acrocentric chromosomes
bioRxiv, January 18, 2023
Guarracino A, Buonaiuto S, de Lima LG, Potapova T, Rhie A, Koren S, Rubinstein B, Fischer C, Gerton JL, Phillippy AM, Colonna V, Garrison E
Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation
bioRxiv, January 15, 2023
Kolmogorov M … Rhie APhillippy AM … Paten B
A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes
BMC Biology, November 8, 2022
Toh H … Rhie A, Phillippy AM … Bukhman YV