Adam Phillippy, PhD

Investigator

adam.phillippynih.gov

Adam began his career at The Institute for Genomic Research in 2001, followed by graduate studies at the University of Maryland starting in 2005. After receiving his PhD in 2010, he started a research group at the National Bioforensic Analysis Center, and later moved to the National Human Genome Research Institute in 2015 to form the Genome Informatics Section. He has made foundational contributions to bioinformatics, specifically in the areas of genome alignment, genome assembly, and microbial forensics. Most recently, he has pioneered the use of single-molecule and nanopore sequencing for the accurate reconstruction of complete genomes at low cost.

Projects

MetaMaps

Long-read metagenomic analysis

SALSA

A tool to scaffold long read assemblies with Hi-C data

MashMap

A fast and approximate long read mapper

Canu

A single molecule sequence assembler for genomes large and small
News posts

De novo assembly of haplotype-resolved genomes with trio binning

October 22, 2018

Human genome assemblies with nanopore, an update

May 23, 2018

We are hiring!

October 4, 2017

Mash Screen: what's in my sequencing run?

September 25, 2017
Publications
A chromosome-scale assembly of the major African malaria vector Anopheles funestus
bioRxiv, December 10, 2018
Ghurye J, Koren S, Small ST, Redmond S, Howell P, Phillippy AM, Besansky NJ
Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation
bioRxiv, December 9, 2018
Bickhart D, Watson M, Koren S, Panke-Buisse K, Cersosimo LM, Press MO, Van Tassell CP, Van Kessel JAS, Haley BJ, Kim SW, Heiner C, Suen G, Bakshy K, Liachko I, Sullivan ST, Ghurye J, Pop M, Weimer PJ, Phillippy AM, Smith TPL
High-throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
Nature Communications, November 30, 2018
Jain C, Rodriguez-R LM, Phillippy AM, Konstantinidis KT, Aluru S
Improved reference genome of Aedes aegypti informs arbovirus vector control
Nature, November 14, 2018
Matthews BJ … Koren SPhillippy AM, Vosshall LB