Adam Phillippy, PhD

Senior Investigator

adam.phillippynih.gov

Adam began his career at The Institute for Genomic Research (TIGR) in 2001, followed by graduate school at the University of Maryland from 2005 to 2010 under the advising of Dr. Steven Salzberg. After receiving his PhD in computer science, he established a bioinformatics research group at the National Biodefense Analysis and Countermeasures Center (NBACC) and in 2015 moved his lab to the National Human Genome Research Institute (NHGRI), where it currently resides. He has made foundational contributions to bioinformatics, specifically in the areas of genome alignment, genome assembly, and microbial forensics. Early in his career he made key contributions to the FBI's genomic investigation of the 2001 anthrax attacks, and most recently he pioneered the use of single-molecule and nanopore sequencing for the accurate reconstruction of complete genomes. For this work he was awarded the Presidential Early Career Award for Scientists and Engineers in 2019.

Software

Merqury

Evaluate genome assemblies with k-mers and more

MetaMaps

Long-read metagenomic analysis

SALSA

A tool to scaffold long read assemblies with Hi-C data

HLA*PRG:LA

Fast and efficient HLA typing from whole-genome sequencing data
News posts

The complete sequence of a human genome

July 23, 2021

The (near) complete sequence of a human genome

September 22, 2020

We are hiring!

September 21, 2020

De novo assembly of haplotype-resolved genomes with trio binning

October 22, 2018
Publications
Epigenetic Patterns in a Complete Human Genome
bioRxiv, May 27, 2021
Gershman A, Sauria ME, Hook PW, Hoyt SJ, Razaghi R, Koren S, Altemose N, Caldas GV, Vollger MR, Logsdon GA, Rhie A, Eichler EE, Schatz MC, O’Neill RJ, Phillippy AM, Miga KH, Timp W
Segmental duplications and their variation in a complete human genome
bioRxiv, May 26, 2021
Vollger MR, Guitart X, Dishuck PC, Mercuri L, Harvey WT, Gershman A, Diekhans M, Sulovari A, Munson KM, Lewis AM, Hoekzema K, Porubsky D, Li R, Nurk S, Koren S, Miga KH, Phillippy AM, Timp W, Ventura M, Eichler EE
Reference genome and demographic history of the most endangered marine mammal, the vaquita
Molecular Ecology Resources, May 21, 2021
Morin PA … Phillippy A, Rhie A … Jarvis ED