Alexander Dilthey, PhD

Guest Researcher

Alexander.Diltheymed.uni-duesseldorf.de

Alexander studied Computer Science in Germany and Switzerland and has a DPhil in Statistical Genetics from the University of Oxford (2012). He co-founded two companies, Peptide Groove LLP and Lighthouse Cancer Diagnostics Ltd. Since 2016 he is back in academia, first as a visiting fellow at NIH/NHGRI and now leading his own research group at the Institute of Medical Microbiology at the University Hospital of Dusseldorf. His research interests include assembly of the human genome's most complex regions (rDNA, KIR, HLA), immunogenetics and the development of "digital" approaches to detecting and treating disease. He maintains a guest researcher position with the Genome Informatics Section.

Projects

HLA*PRG:LA

Fast and efficient HLA typing from whole-genome sequencing data

MashMap

A fast and approximate long read mapper
News posts

Fast and highly accurate HLA typing by linearly-seeded graph alignment

March 22, 2017
Publications
Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing
Nucleic Acids Res, July 27, 2018
Kim JH, Dilthey AT, Nagaraja R, Lee HS, Koren S, Dudekula D, Wood III WH, Piao Y, Ogurtsov AY, Utani K, Noskov V, Shabalina SA, Schlessinger D, Phillippy AM, Larionov V