Arang Rhie, PhD
Staff Scientist
arang.rhie
nih.gov
Arang received a BS in computer science in 2009 and MS in bioinformatics in 2011 from Ewha Womans University. She completed her PhD in 2017 at the Genome Medicine Institute, Department of Biomedical Science, Seoul National University College of Medicine. Her dissertation research aimed to build the first high-quality Korean reference genome for use in medical diagnostics. After her post-doctoral training in the Genome Informatics Section at NIH/NHGRI, she is continuing her research as a staff scientist, focusing on the reconstruction and evaluation of true haplotypes from long-read sequencing and other emerging technologies. She is an active member of the Vertebrate Genomes Project (VGP), Earth Biogenome Project (EBP), Human Pangenome Reference Consortium (HPRC) and the Telomere-to-Telomere consortium (T2T).
Merqury
Evaluate genome assemblies with k-mers and more
Winnowmap
A long-read mapping algorithm optimized for mapping ONT and PacBio reads to repetitive reference sequences.
SALSA
A tool to scaffold long read assemblies with Hi-C data
Canu
A single molecule sequence assembler for genomes large and small
Biobank-scale genotyping of Robertsonian translocations reveals hidden structural variation on the human acrocentric chromosomes
bioRxiv, March 10, 2026
Rhie A, Kim J, Rodriguez-Algarra F, Solar S, Koren S, Antipov D, Wilczewski CM, Maxwell GL, Gerton J, Paschall J, Potapova T, Wolfsberg TG, Singh S, del Castillo del Rio SO, Human Pangenome Reference Consortium, Turner C, Rakyan VK, Phillippy AM
The complete genome of the KOLF2.1J reference iPSC line
Origin and evolution of acrocentric chromosomes in human and great apes
bioRxiv, December 23, 2025
Solar SJ, Hebbar P, Gomes de Lima L, Sweeten A, Rhie A, Potapova T, de Gennaro L, Guarracino A, Kim J, Pickett BD, Paten B, Wilson MA, Koren S, Garrison E, Eichler EE, Ventura M, Gerton JL, Phillippy AM
A trio-binned, haplotype-resolved genome sequence of the zebrafish, Danio rerio Hamilton 1822, SAT strain
Wellcome Open Research, December 22, 2025
Howe K, Rhie A, Koren S, Busch-Nentwich E, McCarthy SA, Wood JMD, Smith M, Myers G, Oliver K