Arang Rhie, PhD

Staff Scientist

arang.rhienih.gov

Arang received a BS in computer science in 2009 and MS in bioinformatics in 2011 from Ewha Womans University. She completed her PhD in 2017 at the Genome Medicine Institute, Department of Biomedical Science, Seoul National University College of Medicine. Her dissertation research aimed to build the first high-quality Korean reference genome for use in medical diagnostics. After her post-doctoral training in the Genome Informatics Section at NIH/NHGRI, she is continuing her research as a staff scientist, focusing on the reconstruction and evaluation of true haplotypes from long-read sequencing and other emerging technologies. She is an active member of the Vertebrate Genomes Project (VGP), Earth Biogenome Project (EBP), Human Pangenome Reference Consortium (HPRC) and the Telomere-to-Telomere consortium (T2T).

Software

Merqury

Evaluate genome assemblies with k-mers and more

Winnowmap

A long-read mapping algorithm optimized for mapping ONT and PacBio reads to repetitive reference sequences.

SALSA

A tool to scaffold long read assemblies with Hi-C data

Canu

A single molecule sequence assembler for genomes large and small
News posts

A complete Y chromosome

August 23, 2023
Publications
Complete de novo assembly and re-annotation of the zebrafish genome
bioRxiv, November 17, 2025
Okendo J, Koren S, Rhie A, Torrado-Tapias A, Pickett BD, Brooks SY, Bouffard GG, Crawford JK, Sison C, Joardar VS, Murphy TD, Tierney JAS, Haggerty L, Martin FJ, Wilson C, Amores A, Postlethwait JH, Murphy J, Sakai N, Varga ZM, Phillippy AM, Burgess SM
Bighorn sheep T2T genome assembly reveals differences in immune genes: a potential cause of high morbidity due to respiratory pathogens
bioRxiv, October 2, 2025
Olagunju TA … Rhie A, Koren S, Phillippy AM … Murdoch BM